Summary of Diuretic Agents 

Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction

CARBONIC ANHYDRASE INHIBITORS

• Acetazolamide, others

SGLT2 INHIBITORS

 • Canagliflozin

 • Dapagliflozin, empagliflozin

LOOP DIURETICS

 • Furosemide

 • Bumetanide, torsemide

 • Ethacrynicacid

THIAZIDES

 • Hydrochlorothiazide

 • Metolazone

 • Chlorothiazide

 • Chlorthalidone

POTASSIUM-SPARING DIURETICS

 • Spironolactone

 • Amiloride

 • Eplerenone

 • Triamterene

OSMOTIC DIURETICS

 • Mannitol

VASOPRESSIN (ADH) ANTAGONISTS

 • Conivaptan

 • Tolvaptan



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