A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on medicine and the patient. Herein, viewers can learn about possible risk factors, management recommendations, treatments, and comorbidities of atopic dermatitis. 



Atopic Dermatitis (AD) is a chronic, relapsing, inflammatory skin disease, affecting greater than 15% of children worldwide. This disease imposes a considerable burden on the physical, mental, and overall well-being of the patient. A combination of dysfunction of the skin barrier, cytokines, chemokines, and receptors in the skin result in the development of AD.



#management #medications #treatment #diagnosis #causes #atopy #atopic #dermatitis

#eczema #dermatology #skinrash



References:

Danby SG, Brown K, Wigley AM, et al. The Effect of Water Hardness on Surfactant Deposition after Washing and Subsequent Skin Irritation in Atopic Dermatitis Patients and Healthy Control Subjects. J Invest Dermatol. 2018;138(1):68-77.



Gdalevich M, Mimouni D, David M, Mimouni M. Breast-feeding and the onset of atopic dermatitis in childhood: a systematic review and meta-analysis of prospective studies. J Am Acad Dermatol. 2001;45(4):520-527.



Petersen EBM, Skov L, Thyssen JP, Jensen P. Role of the Gut Microbiota in Atopic Dermatitis: A Systematic Review. Acta Derm Venereol. 2019;99(1):5-11.



Hui RL, Lide W, Chan J, Schottinger J, Yoshinaga M, Millares M. Association between exposure to topical tacrolimus or pimecrolimus and cancers. Ann Pharmacother. 2009;43(12):1956-1963.



Peroni DG, Piacentini GL, Cametti E, Chinellato I, Boner AL. Correlation between serum 25-hydroxyvitamin D levels and severity of atopic dermatitis in children. Br J Dermatol. 2011;164(5):1078-1082.



Taheri A, Cantrell J, Feldman SR. Tachyphylaxis to topical glucocorticoids; what is the evidence? Dermatol Online J. 2013;19(7):18954.



Mehta AB, Nadkarni NJ, Patil SP, Godse KV, Gautam M, Agarwal S. Topical corticosteroids in dermatology. Indian J Dermatol Venereol Leprol. 2016;82(4):371-378.



Okwundu N, Cardwell LA, Cline A, Unrue EL, Richardson IM, Feldman SR. Topical corticosteroids for treatment-resistant atopic dermatitis. Cutis. 2018;102(3):205-209.



Hindley D, Galloway G, Murray J, Gardener L. A randomised study of "wet wraps" versus conventional treatment for atopic eczema. Arch Dis Child. 2006;91(2):164-168.



Sandhu JK, Wu KK, Bui TL, Armstrong AW. Association between atopic dermatitis and suicidality: A systematic review and meta-analysis. JAMA Dermatol. 2019;155(2):178-187.



Schmitt J, Buske-Kirschbaum A, Tesch F, et al. Increased attention-deficit/hyperactivity symptoms in atopic dermatitis are associated with history of antihistamine use. Allergy. 2018;73(3):615-626.



Pedersen MS, Benros ME, Agerbo E, et al. Schizophrenia in patients with atopic disorders with particular emphasis on asthma: A Danish population-based study. Schizophr Res. 2012;138(1):58-62.



Ascott A, Mulick A, Yu AM, et al. Atopic eczema and major cardiovascular outcomes: A systematic review and meta-analysis of population-based studies. J Allergy Clin Immunol. 2019;143(5):1821-1829. doi:10.1016/j.jaci.2018.11.030