Secondary Causes of Hypothermia - Differential Diagnosis Framework



Definition:

- Core temp < 35°C



Infectious:

 - Sepsis



Neuromuscular Disease:

 - Impaired shivering

 - Inactivity

 - Extremes of age

 

Lack of Substrate/Fuel:

 - Malnutrition

 - Thiamine deficiency

 - Hypoglycemia

 

Impaired Central Regulation:

 - CVA

 - SAH

 - Parkinsonism

 - Hypothalamic dysfunction

 - Multiple sclerosis

 - Anorexia nervosa



Endocrine:

 - DKA

 - Adrenal insufficiency

 - Hypothyroidism

 - Hypoglycemia

 - Hypopituitarism

 - Myxedema coma



Drugs:

 - Intoxicants

 - Anxiolytics

 - Antidepressants

 - Anti manic agents

 - Antipsychotics

 - Opioids

 - Oral antihyperglycemics

 - Beta blockers

 - Alpha-adrenergic agonists

 - General anesthetics



Increased Vasodilatation:

 - Drugs

 - Alcohol

 - Toxins

 - Peripheral neuropathies

 - Spinal cord injuries

 

Skin Disorders:

 - Burn

 - Psoriasis

 - Exfoliative dermatitis

 

Other:

 - Environmental Exposure * 

 - Pancreatitis

 - Carcinomatosis

 - Uremia

 - Vascular insufficiency

 - Multi-system trauma

 - Shock



By Dr. Ravi Singh @rav7ks



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