Causes of Anterior Uveitis - Differential Diagnosis

Anterior Uveitis - 90% of cases of Uveitis

 • Inflammation of middle layer of the eye

 • Anterior-iris +/-ciliary body, Iritis=anterior uveitis

 • Posterior-choroid

 • Panuveitis: anterior chamber, vitreous humor, and retina or choroid

Unilateral

 • Inflammatory: HLA-B27 related - isolated or 2ndary to spondylarthritis, Posner-Schlossman Syndrome

 • Infectious:  HSV and toxoplasmosis (common), VZV, syphilis, TB, post-strep, Immunocompromised-CMV

 • Chronic Inflammatory: Sarcoid, JIA

Bilateral:

 • Inflammatory: Behcet's, SLE, TINU syndrome (w/ renal involvement)

 • Medication: Rifabutin

 • Idiopathic: Unilateral/bilateral up to 30% of cases

 • Mimics: Malignancy - Leukemia/Lymphoma

Pearl: Acute onset anterior uveitis in an elderly patient is likely HSV/VZV. In young patient/ consider HIA B27-related syndrome



- Dr. Ann Marie Kumfer @AnnKumfer



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