Medications for Recurrent Calcium Oxalate (CaOx) Stones

HYPERCALCIURIA

 • Thiazides: HCT, Indapamide, Chlorthalidone

 • Consider after first stone if

    - Single kidney

    - Large stone burden

    ± K citrate

HYPOCITRATURIA

 • Potassium citrate

 • Benefit also outweighs risk in CaPO4 stones

 • Also consider if low UPH

HYPERURICOSURIA (with normal UCa)

 • Allopurinol

 • Mechanism unclear ? Nidus effect

 • No data for hypercalciuric patients

NO ABNORMALITIES (or all addressed)

 • K citrate ± thiazide

 • K citrate preferred first line (lower side-effect profile)



Dr. John Booth @ThePeanutKidney



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