Potential Treatment Agents for Treatment of the Primary Clostridium difficile infection Episode

Proven efficacy:

 • Vancomycin - 125 mg PO qid × 10 days

 • Fidaxomicin - 200 mg PO bid × 10 days

 • Metronidazole - 500 mg PO tid × 10 days

Probable efficacy:

 • Nitazoxanide - 500 mg PO bid × 10 days

 • Fusidic acid - 250 mg PO tid × 10 days

Inadequate data to support efficacy:

 • Rifaximin - 400 mg PO tid × 10 days

 • Tigecycline - 50 mg IV every bid × 10 days

 • Bacitracin - 25000 units PO qid × 10 days



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