Faget's Sign & Liebermeister's Rule
Pulse-Temperature Dissociation
EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM
INFECTIOUS CAUSES
• Legionella
• Psittacosis
• Q Fever
• Typhoid Fever
• Typhus
• Babesiosis
• Malaria
• Leptospirosis
• Yellow Fever
• Viral Hemorrhagic Fevers
• Rocky Mountain Spotted
• Fever
OTHER CAUSES
• Beta Blockers
• CNS Lesions
• Lymphomas
• Factitious Fever
• Drug Fever
CLINICAL UTILITY
1. Legionella
2. Chlamydia
3. Typhoid Fever (S. typhi)
4. Dengue Fever
NOTE:
There is limited predictive value in pulse-temperature dissociation and the most likely infection. However! There are specific cases where it can help hone your differential.
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