Causes of Growth Restriction - Small for Gestational Age - Differential Diagnosis Algorithm

Maternal

 • Chronic Maternal Hypertension

 • Gestational Hypertension

 • Autoimmune Disease

 • Protein-calorie Malnutrition

 • Smoking/Alcohol

 • Substance Abuse

 • Uterine Malformations

 • Hemoglobinopathies (Sickle Cell)

 • Renal Insufficiency

 • Anti-phospholipid Antibodies

Fetal:

 • Constitutionally Small

 • Multiple Gestation

 • Intrauterine Infections

 • Chromosomal Anomaly

 • Genetic Syndromes

 • Congenital Malformations

Placental Insufficiency:

 • Placental/Cord Abnormalities

 • Chronic Abruption

 • Placenta Previa

 • Abnormal Cord Insertion



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