Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm

Structural Defect - Asplenia/HypospIenism

 • Bacteremia/Septic Shock

 • Encapsulated Bacteria

Cell Mediated Immunity - T-Cells Affected

 • Pneumonia

 • Aspergillus

 • Candida

 • Pneumocystis jirovecii

 • CNS Infection

Neutropenia or Neutrophil Dysfunction

 • Aphthous Ulceration

 • Perirectal Infection

 • Abscess Formation

 • Soft Tissue and Visceral lnfection

 • Periodontal Disease

Complement Deficiency

 • Encapsulated Bacteriemia

 • Streptococcus pneumoniae

 • Haemophilus influenzae

 • Neisseria spp.

Hypogammaglobulinemia

 • Recurrent Sinusitis

 • Pneumonia

 • Bronchitis

 • Chronic Diarrhea

 • Giardia Infection



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