Hypothyroidism - Differential Diagnosis Algorithm

Central Hypothyroidism

 • Isolated TSH Deficiency

 • Panhypopituitarism

Thyroid Hormone Resistance

Iatrogenic

Primary Hypothyroidism

 - Transient

     • Subacute Lymphocytic / Granulomatous

     • Thyroiditis

     • Post-Partum Thyroiditis

     • Subtotal Thyroidectomy

 - Infiltrative Disease

     • Fibrous Thyroiditis

     • Hemosiderosis

 - Congenital Thyroid Agenesis/ Degenesis

     • Severe Iodine Deficiency

 - Medications

     • Thionamides

     • Lithium

     • Amiodarone

     • Interferon

 - Central Hypothyroidism

     • Hashimoto's Thyroiditis



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