Hypoglycemia - Differential Diagnosis Algorithm

Fasting Hypoglycemia:

 • Excess Insulin

 • Medications (e.g. Insulin Secretagogues, ß-Adrenergic Antagonists, Quinine, Salicylates, Pentamidine)

 • Alcohol

Post-Prandial (Reactive):

 • Alimentary (e.g. in the setting of Gastric Surgery)

 • Congenital Enzyme Deficiencies

 • Idiopathic

Other Causes:

 • Critical Illness (e.g. Hepatic Failure, Renal Failure, Cardiac Failure)

 • Sepsis

 • Hypopituitarism

 • Adrenal Insufficiency

 • Hyperinsulinemic States (e.g. Glucagon, Catecholamine Deficiency, Insulinoma)

 • Malnutrition/Anorexia Nervosa



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