Primary Hyperthyroidism - Pathogenesis and Clinical Findings



Note: Although rare, gestational diseases can lead to thyrotoxicosis due to excess secretion of hCG, which is structurally similar to TSH. Secondary hyperthyroidism due to excess TSH production by the pituitary can also occur.

Signs/Symptoms:

 - Diarrhea 

 - Nervousness

 - Hyperkinesia

 - Hyperreflexia

 - Tremor

 - Poor attention

 - Incr weight loss

 - Heat intolerance

 - Incr appetite

 - Incr sweating

 - Proptosis

 - Diplopia

 - Lid retraction

 - Conjunctivitis

 - Tachycardia

 - Palpitations

 - Bruit over thyroid

 - Decr exercise tolerance

 - Pretibial myxedema



#Primary #Hyperthyroidism #endocrinology #pathophysiology