Anaphylaxis: Treatments (Acute)

Additional Info:

 • IV steroids may be considered for prevention of late phase reactions. Patients should be monitored in the ED for a minimum of 4-6 hrs.

 • Follow-up with a family physician is suggested within 48hrs. An epinephrine autoinjector prescription should be provided, as well as allergy testing.

 • H2 receptor antagonist use (e.g. Ranitidine), to amplify H1 receptor antagonist responses may be considered. Beta-blockers and IV fluids for blood pressure resuscitation may also be warranted.



Treatment: 

 • Antihistamine (adjunct therapy) e.g. Cetirizine (non-sedating) PO q4-6hrs

 • Epinephrine (1st line treatment) 1:1000 IM q5-10mins, anterolateral thigh

 • Salbutamol (adjunct therapy) e.g. Ventolin inhaler



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