Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings



Psychological Hypothesis

 • Cognitive behavioral model: Emotional disturbance arising from dysfunctional beliefs about situations or stimuli

 • Avoidance/Compulsions maintain maladaptive beliefs and anxiety

Biological Hypotheses

 • Serotonin: Hypersensitivity of postsynaptic serotonin receptors -> Dysregulation of anxiety

 • Structural model: Dysfunction of brain circuits in the oribito-frontal-subcortical regions suspected

Genetics

 • 27-47% heritability in twin studies



-> Obsessive-Compulsive Disorder (OCD)



Obsessions - Unwanted/intrusive thoughts, ideas, images, impulses that intrude into consciousness 

Compulsions - Urges to perform overt behavioural or mental rituals to reduce obsessional anxiety or distress about feared consequences



#OCPD #ObsessiveCompulsive #PersonalityDisorder #Diagnosis #Psychiatry #Signs #Symptoms