Ankylosing Spondylitis: Pathogenesis and Clinical findings

 • Pain in lumbar area and gluteal region: (Dull, insidious onset, becomes more constant as disease progresses) - X-ray: Blurring and pseudo-widening in Sl joints

 • Asymmetrical Oligoarthritis: mostly involving the lower extremities, most commonly the knees

 • Enthesitis: Tenderness over tendon insertion points, most prominently in Achilles, Plantar fascia, and tibial tuberosity 

 • Decr Lumbar spine flexion, Decr Lumbar lordosis, Incr thoracic kyphosis, X-ray: loss of lordosis (straight spinal column)

 • Late complication: ankylosed spine (bamboo spine) -> Fracture of spine with minor trauma



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