Takayasu’s Arteritis: Pathogenesis and clinical findings



 - Fatigue, weight loss, low grade fever, arthralgias

 - Incr ESR, CRP, WBC

 - Aortic aneurysm (with potential for aortic regurgitation), other arterial aneurysms

 - Visual Dysfunction 

 - Orthostasis, Syncope, Headache, Convulsions, TIA/Stroke

 - Angina, Incr risk of Acute Coronary Syndrome

 - >10mmHg systolic pressure difference between arms

 - Abdominal Pain

 - Arm/Leg Claudication (pain with use)

 - Decr palpable pulses in limbs, Often asymmetrical (common)

 - Ischemic Skin Ulcers

 - Bruit (may be heard anywhere. most commonly carotid)

 - Systemic Hypertension



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