Burkitt-Like Lymphoma with 11q Aberration

Clinical

 • Provisional entity

 • Comprises a group of lymphomas that morphologically and immunophenotypically resemble BL but that lack MYC rearrangements and have proximal gains and telomeric losses of llq.

 • Wide age range, more common in children/young adults.

 • More often nodal than BL, more limited disease without CNS or BM involvement

 • Similar lymphomas can be seen in the post-transplant setting.

 • Similar clinical course to BL

Morphology and Immunophenotype

 • Tend to have more pleomorphism than BL, occasionally with a follicular pattem.

 • Characteristic lower expression of CD38 and coexpression of CD16/CD56 by flow.



Dr. Laura Brown @lauraebrown



#BurkittLike #Lymphoma #11q #Aberration #diagnosis #hemepath #pathology