Monoarthritis - Differential Diagnosis

Infection (Acute):

 - S. aureus (most common)

 - S. pneumonia

 - Salmonella (in asplenic patients)

 - Gonococcal infection

Infection (Chronic)

 - Mycobacterial species

 - Lyme disease

Fungal:

 - Histoplasmosis,

 - Coccidioidomycosis

Crystal

 - Gout- usually LE, early in dz, neg birefringent

 - CPPD- Usually involves the knee, but can involve the b/l wrists, pos birefringent

Inflammation:

 - Early Rheumatoid arthritis

 - Seronegative spondylarthritis

 - IBD, reactive arthritis, psoriatic arthritis

 - SLE

 - Sarcoid

 - Erosive OA



Dr. Ann Marie Kumfer @AnnKumfer



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