Marantic Endocarditis 



Epidemiology:

 - Incidence of non-bacterial thrombotic endocarditis (marantic endocarditis if associated with cancer) is largely unknown, though estimated at ~1-1.5%

 - A study of 200 solid-tumor cancer patients with no signs/syrnptoms of embolic events revealed 19% had cardiac valvular vegetations found via TTE. 

 - Lung, Pancreas, Gastric, and Ovarian Adenocarcinoma are most commonly implicated.

Clinical Findings

 - Systemic Ernboli occur in ~50% of patients.

 - Imaging: Typically small <1cm, irregularly shaped vegetations on mitral and aortic valve. These are RARELY associated with valvular degeneration. Vegetations mostly just sit on valve, destruction of valve is very uncommon

 

Bryan Ulrich @BryanCUlrich



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