Possible approach to empiric anticoagulation in COVID-19



Is D-dimer above '"1,000-2,000 ng/ml?

Contraindication to anticoagulation?

Check fibrinogen level and/or thromboelastography (TEG)

Normal or hyper-coagulable pattern (nearly always) -> Therapeutic Anticoagulation

 - R-time low or normal on thromboelastography

 - Fibrinogen level is normal or elevated

Hypo-coagulable pattern (rare, late-stage) -> No Anticoagulation

 - R-time prolonged on thromboelastography

 - Fibrinogen level low



Dr. Josh Farkas @pulmcirt - Internet Book of Critical Care @iBookCC



#empiric #anticoagulation #COVID19 #management #schema #criticalcare #algorithm #SARSCOV2 #Coronavirus