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Description
The recommended pre-operative workup for patients taking anticoagulants involves stratifying both thromboembolic & bleeding risk, determining appropriate timing for medication interruption, & deciding whether bridging therapy is needed. Specific approach depends on the type of anticoagulant, renal function, and procedure-related bleeding risk. • Direct Oral Anticoagulants (DOACs) o For apixaban, rivaroxaban, and Edoxaban, the American College of Chest Physicians recommends stopping these agents 1-2 days before low-to-moderate bleeding risk procedures and 2 days before high bleeding risk procedures. • For dabigatran, interruption timing depends on renal function. o With normal renal function (CrCl ≥50 mL/min), stop 1-2 days before low-risk procedures and 2 days before high-risk procedures. o With impaired renal function (CrCl <50 mL/min), extend interruption to 3-4 days before high-risk procedures due to predominantly renal clearance. #apixaban #rivaroxaban #Edoxaban #dabigatran #DOACs #preoperative #perioperative #Warfarin #CHA₂DS₂-VASc #antithrombotic #anticoagulant #guidelines
Contributed by
Satyendra Dhar, MD
@DharSaty
Hospital Medicine Clinical Assistant Professor The content and images on this website are provided for educational and informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. The views expressed are those of the authors and do not necessarily reflect those of any affiliated institutions. While efforts are made to ensure accuracy and currency, medical knowledge is continually evolving, and errors or omissions may occur. Users are advised to independently verify information and seek guidance from qualified healthcare professionals for any medical decisions. By using this website, you acknowledge responsibility for your own clinical judgments, and the website and its contributors disclaim any liability arising from the use of its content. 👉 Follow 'Medical Infographics' on 👉 https://www.DharSaty.com
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