Wernicke's Encephalopathy 

CLINICAL TRIAD: only seen in 1/4 pts 

W.E. is often under diagnosed 

1. ENCEPHALOPATHY (82%) 

Disorientation, Indifference, Inattentiveness. 5% have decr LOC 

2. OCCULOMOTOR DYSFUNCTION (29%) 

Nystagmus, Lateral Rectus Palsy, Conjugate Gaze Palsy, INO, Unequal Pupils, Light near dissociation, Nonreactive pupils, etc 

3. GAIT ATAXIA (23%) 

Primarily: Stance & gait 

Unlike Alcoholic Cerebellar Degeneration W.E. has no upper limb ataxia 

OTHER: peripheral neuropathy, hypothermia, cardiac, vestibular 



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