Phases of Colchicine Toxicity

 - Early Phase (0-24h) 

 - Multi-organ failure Phase (1-7 days) 

 - Recovery Phase (7-21 days)



Respiratory: Respiratory Distress Syndrome

Cardiovascular: Congestive heart failure, Cardiac arrhythmia, cardiac arrest

Neurologic: Seizures, Encephalopathy, Cerebral edema, myopathy

Hematologic: Cytopenias, Bone marrow suppression, Hemolysis, DIC

Metabolic: Metabolic acidosis, HypoK, hypoNa, hypoP04, hypoglycemia/hyperglycemia

Other: Renal failure, Liver failure, Immune compromise & Sepsis 



By Dr. Kathryn Watson @Kat_Watson



#Colchicine #Toxicity #Toxicology #Phases #Pharmacology #Diagnosis