Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban - 75% Hepatic, 25% Renal
Dabigatran - 20% Hepatic, 80% Renal
Edoxaban - 50% Hepatic, 50% Renal
Rivaroxaban - 65% Hepatic, 35% Renal

#DOAC #NOAC #Metabolism #Pharmacology #Clearance #oral #anticoagulation