Loop Diuretic Conversion - Dose Equivalents

Bumex (bumetanide) 1 mg PO

Demadex (torsemide) 20 mg PO

Lasix (furosemide) 40 mg PO

Lasix (furosemide) 20 mg IV



Loop diuretics are given their name due to the site of action being the Loop of Henle. However, it's important to remember the specific site of action for your board exams, that is the ASCENDING loop of Henle, not the descending. There are 3 loop diuretics which have the dose conversion of 1:20:40 mg. Furosemide is the most commonly used to treat edema and is a 1:2 ratio of IV:PO. If patient's do not respond well to furosemide, changing to bumetanide or torsemide may be effective as they have higher bioavailability than furosemide.



Jarred Prudencio, PharmD - https://www.instagram.com/ambcarerx



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