Medications for High-Altitude Sickness 

Acetazolarnide 

 • Carbonic Anydrase Inhibitor Bicarb diuresis & metabolic Acidosis -> compensatory hyperventilation 

Dexamethasone 

 • Decrease vasogenic edema 

 • Decrease intracranial pressure 

 • Anti-emetic 

O2 (SaO2 > 90%) 

 • Improves hypoxemia 

Nifedipine 

 • Decreases pulmonary arterial pressure 

Hyperbaric O2 

 • Improves hypoxemia 



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