High Flow Nasal Cannula

Putative beneficial mechanisms of high flow nasal cannula (HFNC) 

oxygen therapy. EELV, end-expiratory lung volume; FiO2, inspiratory oxygen fraction; Temp., temperature.

 • Nasopharyngeal CO2 washout 

 • Decreased anatomical dead space 

 • Maintenance of mucociliary function 

 • Positive airway pressure 

 • Increased airway calibres 

 • Decreased hydrostatic capillary-alveolar gradient 



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