Toxic Megacolon 

Inflammatory bowel disease or Infectious colitis characterized by total or segmental nonobstructive colonic dilatation + Systemic toxicity 

Clinical diagnosis:

Radiographic evidence of colonic distension PLUS at least 3 of the following: 

• Fever > 38

• HR > 120 

• WBC> 10.5 

• Anemia 

PLUS at least 1 of the following: 

• Dehydration 

• Altered sensorium 

• Electrolyte disturbances 

• Hypotension 

Management:

• Supportive care 

• Treat underlying condition 



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