Antibiotics - Mechanisms and Sites of Action 


Inhibit Cell Wall Synthesis or Function 
- Beta Lactams, Vancomycin, Daptomycin, Polypeptides 


Inhibit Protein Synthesis 50S subunit 
- Macrolides, Clindamycin, Linezolid, Streptogramins, Chloramphenicol 

 
Inhibit Protein Synthesis 30S Subunit 
- Aminoglycosides, Tetracyclines, Tigecycline 
Inhibit Nucleic Acid Synthesis or Function 
Inhibit DNA Gyrase +/- Topoisomerase IV: Quinolones 
Inhibits Folate Synthesis: Trimethoprim / Sulfamethoxazole 
Create Free Radicals: Metronidazole, Nitrofurantoin 


- Dr. Eric Strong @DrEricStrong - Strong Medicine


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