Paracoccidioides brasiliensis Lymphadenitis: 


Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in Latin America. Head&neck, Lymph Nodes, and lungs are commonly involved. 


Lymph node entirely replaced with fibrosis 

(A) and well-formed granulomas (B). Yeast 

forms (arrows) can be seen within giant cells 

on H&E (C) or highlighted by GMS special 

stain (D). Note the characteristic pilot's 

wheel-like appearance of the budding 

yeasts. 
Contributor: Dr. Geronimo Jr. 
@EC_SocforHemepath @GeronimoJrLapac 


#Paracoccidioides #brasiliensis #Lymphadenitis #Pathology #LymphNode #Clinical #Microscopy