Linezolid (Zyvox) (PO and IV) - Antibiotics Class Overview


Mechanism: Oxazolidinone class –unique ribosomal inhibitor (acts on 50S subunit).  Bacteriostatic agent.
Spectrum: covers all Gram positives including strep, MRSA and VRE.  Also has good activity vs tuberculosis.  
Used for:  skin/soft titssue infections, HAP/HCAP/VAP with suspected MRSA, VRE infections


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