#Visualabstract for the BICAR-ICU trial LANCET 



"Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial" 

VOLUME 392, ISSUE 10141, P31-40, JULY 07, 2018 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)31080-8/fulltext



Conclusion: In patients with severe metabolic acidaemia, sodium bicarbonate had no effect on the primary composite outcome. However, sodium bicarbonate decreased the primary composite outcome and day 28 mortality in the a-priori defined stratum of patients with acute kidney injury.



#Bicarbonate #BICARICU #Acidemia #Acidosis #VisualAbstract #EBM