Limbic system

Medial/rostral hypothalamus

Lateral hypothalamus

Hypothalamic neurosecretion

ADH

Autonomic centers

Signal generator

CRH

Negative feedback

Sympathetic nervous system

Anterior pituitary

ACTH

Adrenal medulla

Adrenal cortex

#Cortisol

#Epinephrine (norepinephrine)

Response to signal (hormone release)