ACA Colorectal Cancer Screening Guidelines



When to Screen?

When to Stop?

Family History



Performance Characteristics for Colorectal Cancer Screening Tests

Stool/blood-based tests:

 • FIT: 79% sensitivity, 94% specificity for CRC

 • Multitarget stool DNA test: 92% sensitivity, 87% specificity for CRC, Long term reduction in CRC incidence unknown

 • Septin 9: 48% sensitivity, 91% specificity for CRC

Direct visualization:

 • Colonoscopy: 100% detection rate for CRC, Long term reduction in CRC incidence of 31-71%, mortality 65-88%

 • Flexible sigmoidoscopy: 90-100% sensitivity for distal CRC, Long term reduction in CRC incidence 21%, mortality 26%

 • CT colonography: 90-100% sensitivity for CRC, Poor sensitivity for flat lesions or SSLs

 • Colon capsule: 81% sensitivity, 93% specificity for polyps >6mm



by Dr. Chaitanya Allamneni @CAllamneni via @EmoryGastroHep



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