Hemophilia A Prophylaxis (Factor Eight Deficiency)



Who Needs Prophylaxis?



Primary Prophylaxis:

 • Severe deficiency (activity level <1%) even without hx of bleeding episodes

Secondary Prophylaxis:

 • 2 bleeding episodes

 • Mild-to-moderate (Activity 5-40%): consider intermittent ppx

 • Severe: continuous ppx

Tertiary Prophylaxis:

 • Documented arthropathy

 • Continuous ppx regardless of severity



Dr. Jonathan Berry @jlberrymd



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