Digoxin 101 - Pharmacology

Indications:



1) Tachyarrhythmias 

 • Atrial Fibrillation, Atrial Flutter, Supraventricular Tachycardias

 • ↑ Vagal tone, ↑ baroreceptor sensitivity leads to AV nodal delay (ie rate control)



2) Heart Failure, reduced EF

 • If NYHA III or IV symptoms despite GDMT

 • Na/K Pump Inhibition - ↑ buildup of intracellular calcium leads to more cardiac contractility (ie inotropy)



Matt Tsai @thematttsai



#Digoxin #Pharmacology #cardiology