Oxygen-Hemoglobin Dissociation Curve



Left Shift (↓ O2 unloading to tissue), Left = Lower:

 • ↓ H+ (↑ pH)

 • ↓ PCO2

 • ↓ 2,3-BPG

 • ↓ Temperature



Right Shift (↑O2 unloading to tissue):

 • ↑ H+ (Acid)

 • ↑ PCO2

 • Exercise

 • ↑ 2,3-BPG

 • High Altitude

 • ↑Temperature



Matthew Ho, MD PhD @MatthewHoMD



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