Whipple Disease (Tropheryma whipplei) - Diagnostic Algorithm



Whipple's disease suspected:

 • Arthralgias, weight loss, abdominal pain, diarrhea

 • Seronegative migratory polyarthritis refractory to immunosuppression

 • Unexplained progressive CNS disease/early-onset cognitive deficits

 • Fever of unknown origin, chronic serositis, unexplained generalized lymphadenopathy



Matthew Ho, MD PhD @MatthewHoMD



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