Whipple Disease (Tropheryma whipplei) - Diagnostic Algorithm Whipple's disease suspected: • Arthralgias, weight loss, abdominal pain, diarrhea • Seronegative migratory polyarthritis refractory to immunosuppression • Unexplained progressive CNS disease/early-onset cognitive deficits • Fever of unknown origin, chronic serositis, unexplained generalized lymphadenopathy Matthew Ho, MD PhD @MatthewHoMD #Whipple #Disease #diagnosis #algorithm #Tropheryma #whipplei