Algorithmic Approach to Acute Interstitial Nephritis

When to suspect AIN? (not sensitive)

 • AKI, AKD, rapidly progressive CKD of unclear etiology; oliguria

 • Classic triad (<10%): fever, rash, eosinophilia

 • UA: sterile pyuria, WBC casts, eosinophiluria, microscopic hematuria, mild tubular proteinuria, granular casts/RTE; blend sediment

 • Received drug associated with AIN



Matthew Ho, MD PhD @MatthewHoMD



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