Magnesium Deficiency and Alcoholism
Risks associated with Mg deficiency in alcoholism:
• Affects protein synthesis. energy production, & cell function.
• Contributes to increased HTN, atherosclerotic CVS disease & osteoporosis.
• Predisposing factor for the development of alcohol-induced pathologies such as cardiomyopathy, sarcopenia, CVA & cirrhosis.
• Depressive symptoms among alcoholics, especially during the withdrawal period can be attributed to Mg deficiency where Mg regulates the calcium ion stream towards the neuronal calcium channels.
• Mg deficiency is shown to increased platelet aggregation that was normalized with Mg therapy & this antiplatelet effect may be related to the finding that Mg inhibits the synthesis of thromboxane A2 and 12-hydroxyeicosatetraenoic acid, & eicosanoids.
Satyendra Dhar, MD @DharSaty
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