High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK



Glycols - ethylene and propylene glycol

Oxoproline - associated with acetaminophen use

L-lactate - produced during hypoxic metabolism

D-lactate - associated with short bowel syndrome

Methanol ingestion - anti-freeze, varnish, etc.

Aspirin - salicylate toxicity causes lactic & ketoacidosis

Renal failure  - underexcretion of acids in advanced renal failure

Ketoacidosis - diabetic, alcohol, starvation



Paresh Jadav, MD @jadav_md



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