Acute Diarrhea - Differential Diagnosis Framework
1)  Diagnostic studies only for dysentery, severe disease, >7 days
2) PCR>culture
3) Empiric antibiotics NOT recommended 

Infectious - Non-Invasive:
 • Viral: Norovirus, Rotavirus, Adenovirus, Astrovirus
 • Bacterial: Clostridium perfingens, Staph aureus, Bacillus cereus, ETEC, EPEC, Listeria monocytogenes, Vibrio cholerae, Tropheryma whipplei
 • Protozoal: Giardia lamblia, Cryptosporidium, Cystisospora belli, Cyclospora
Infectious - Invasive: Clostridium difficile, Campylobacter, EHEC, EIEC, Shigella, Salmonella, Yersinia, Vibrio parahaemolyticus, Entamoeba histolytica, Cytomegalovirus
Non-Infectious: Medications, Acute abdominal processes, Lactose intolerance, Constipation with overflow

by Lauren Banaszak, MD @LaurenBzak via @uw_IMresidency

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