Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
• Urine Na <20: Extra-renal losses
• Urine Na >30: Renal losses, Cerebral salt wasting
Euvolemic, Serum uric acid <4
• SIADH, Hypothyroidism, Low solute intake, Glucocorticoid deficiency, Primary polydipsia
Hypervolemic, Serum uric acid >4
• Urine Na < 20: Heart failure, Cirrhosis, Nephrotic syndrome
• Urine Na > 30: Renal failure
Satya Patel, MD @SatyaPatelMD
#Volume #Hyponatremia #algorithm #diagnosis #sodium #low #nephrology