Irritable Bowel Syndrome (IBS) - Management
Global IBS Symptoms:
  - Limited trial low FODMAP diet
  - Soluble, viscous, poorly fermentable fiber
  - Peppermint oil (Menthe piperita)
  - Tricyclic Antidepressants
  - Gut-directed psychotherapies
IBS-D:
  - Rifaximin- up to 3 courses
  - Alosetron 0.5-1 mg BID in ♀ with severe symptoms who failed conventional tx
  - Mixed opioid agonists/antagonists (eluxadoline 75-100mg QD)
IBS-C:
  - Secretagogues → activate receptors on apical membranes of intestinal epithelial cells intestinal secretion & peristalsis
  - 5-HT4 (Serotonin) agonist tegaserod 6mg BID in ♀ <65yo with 1 cardiovascular risk factors who failed secretagogues

by Tina Hang, MD @TinaPhamHang via Emory Gastroenterology and Hepatology @EmoryGastroHep

#IBS #Irritable #Bowel #Syndrome #Management #gastroenterology #treatment