Adrenal Insufficiency Diagnosis Algorithm Test 1: Baseline AM Cortisol - Beware of major normal value - variation between assays - Assay cross reacts with hydrocortisone - Falsely elevated in high globulin levels (OCPs, pregnancy) Test 2: ACTH Stimulation - Cutoffs are the same as above - Do NOT use incremental increase to assess response BCM IM Residency @BCM_InternalMed #Adrenal #Insufficiency #Diagnosis #Algorithm #endocrinology
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