Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin, Scl70 (in some cases)
Speckled pattern:
 • SjS, SLE, DM, SSc, PM/SSc OS, MCTD, UCTD
 • Smith, Sm/RNP, Scl-70, SSA-52 (Ro52), SSA-60 (Ro60), SSB (La), RNA polymerase III, Ku
Centromere pattern:
 • SSc, PBC/SSc OS
 • CENP-A, CENP-B
Nucleolar pattern:
 • SSc, PM/SSc OS, Raynaud phenomenon, SjS, cancer, other SARD
 • Fibrillarin, RNA polymerase III, PM/Scl100, Th/To, Scl-70 (in some cases)
Nuclear dots pattern:
 • PBC, DM, other inflammatory conditions
 • Sp-100, PML, NXP-2 (MORC3 or MJ)

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