Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated - DAT: IgG positive, C3 positive or negative - Smear: spherocytes Cold AIHA: - 20%; IgM mediated - DAT: IgG negative, C3 positive - Smear: agglutination, rouleaux BWH Medicine Residency @BrighamMedRes #AIHA #Autoimmune #Hemolytic #Anemia #Pathophysiology #diagnosis #hematology
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