Therapeutic Plasma Exchange - Circuit Diagram
Goal = removal of abnormal/excess cells or substances that:
 • Have a long half life
 • Acutely toxic/resistant to conventional therapy
 • Large enough to be removed by pheresis
Example:
 • Autoantibody
 • Immune complex
 • Cryoglobulin
 • Myeloma light chains
 • Endotoxin
 • Cholesterol-containing lipoprotein

BWH Medicine Residency @BrighamMedRes

#Plasma #Exchange #pathophysiology