Lymphadenopathy - Differential Diagnosis Algorithm
Localized:
• Cervical: EBV, CMV, HIV, Toxo, TB, Lymphoma, Head / Neck scc, Melanoma
• Axillary: Infection (Cat scratch, Tularemia), Breast Cancer
• Supraclavicular: Virchow's Node, Thoracic or Abdominal cancer, Thyroid / larynx disease, Tuberculosis
• Inguinal: Sexually transmitted infections (STl)
Generalized:
• Auto-immune: Dermatomyositis, Rheumatoid Arthritis, Sjögren's
• Infection: Acute HIV, EBV, Mycobacterial - disseminated tuberculosis
• Malignant: Lymphoma, Angioimmunoblastic T-cell lymphoma
• Miscellaneous: Castleman's, Sarcoidosis
• Medications: Allopurinol, Beta-Blockers, Anti-epileptic drugs (AEDs)
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