Fusarium Treatment
 • Antifungal "susceptibility" can vary with Fusarium spp
 • F. oxysporum: low MICS to amphotericin
 • F. solani: higher in vitro MICS for amphotericin
 • Prognosis and response to antifungals is tied to immune status
 • Recovery of neutropenia is key > uniformly lethal without this
Therapeutic options for disseminated disease:
 • Optimal treatment not established, no prospective trials
 • Most experts recommend lipid formulations of amphotericin B for severe cases; triazole (e.g., voriconazole, posaconazole, isavuconazole) for mild/moderate
Tx in setting of endophthalmitis:
 • Surgical removal of vitreous (vitrectomy) is nearly always necessary
 • Depending on the type of injury (i.e. open globe), pt might require enucleation

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